In 1861, a Girls’ School was founded in Metsovo thanks to a donation from Eleni Tossizza. Until that time, most Metsovo women did not speak Greek.
Doctor Spyridon Sokolis, who worked in Metsovo during the mid-19th century, mentions that after the founding of the school, «…students showed immense progress in both language studies and handiwork…»
He also noted that men spoke Greek well thanks to their commercial activities and their continuous contact with Ioannina and Trikala.
During the 19th century, there were five schools in Metsovo: a kindergarten, a girls’ school, two primary schools and a “Scholarhio”, where students could attend the two first years of high school.