1430 1430-1912: OTTOMAN RULE
1430 On October 9, Ioannina surrendered to Sinan Pasha, beylerbey (administrator) of Rumeli. It was the beginning of Ottoman rule across large part of Epirus.
1455 According to the census carried out by the Ottomans in 1454-55, Metsovo is inhabited by 700 families subject to taxation, 41 widows and 52 single men and women.
1617 On May 17, Nikolaos Mpasdanis (known as Vlachonikolas from Metsovo) was executed in Trikala for converting back to Christianity from Islam.
1659 In 1659, Sultan Mehmed IV granted tax and political privileges to the residents of Metsovo due to the services they offered as "derbentzides" (guards of "derveni"/mountain pass).
1659 The Exarchate of Metsovo was founded and was supervised by the Patriarchate of Constantinople.
1680 A voivode (high-rank Ottoman officer) was nominated to head the administration of Metsovo in the 17th century.
1719 The French built a storehouse in Metsovo and filled it with products made by the Vlach population that they planned to export.
1759 On May 25, the Greek school of Metsovo was officially founded thanks to a donation from Sterios Stanos.
1787 Ali Pasha became the administrator (Derbendler) of the Trikala sanjak area to which Metsovo belonged. He then became the Pasha of Ioannina.
1795 Ali Pasha created the mukataa (tax district) of the Metsovo area.
1818 The Exarchate of Metsovo was passed to the School of Greek Language (Greek school) of Metsovo.
1821 1821-1828 Greek Revolution
1830 The independent Greek state was founded, with its borders extending to Epirus and Thessaly.
1831 Metsovo becomes a nahiye (municipality) and is officially incorporated into the Ioannina pashalik. For the first time a Turkish administrator (muhafiz) is put in charge.
1840 A fire destroyed the Greek School that had been built thanks to a donation from Dem. Zamanis. The library, containing 4000 books and manuscripts, was razed. After the incident, the school operated in the cells of the church of Aghia Paraskevi.
1850 A müdir (nahiye administrator) was established in Metsovo in around 1850.
1853 Nikolaos Stournaras, one of Greece's national benefactors, died in Halkida.
1854 In 1854, during the Crimean War, revolutionary movements emerged in Epirus under the leadership of General Theodoros Grivas.
1856 Michael Tossizza, one of Greece's national benefactors, died in Athens.
1864 In 1864-67 the fort of Metsovo was built, incorporating a mosque.
1867 The area of Metsovo temporarily became a kaza.
1870 In the early 1870s, the "Averoff pharmacy" was founded in Metsovo. It provided the entire city and the residents of the wider area, including soldiers of the Turkish guard, with free medicine.
1875 The area of Metsovo permanently became a kaza; a kaymakam (deputy governor) and a kadı (judge) were also established there. In total, it incorporated approximately 6,000 residents.
1878 Under the pretext of the Russian-Turkish war, a revolt broke out in Epirus that led to a rise in guerrilla warfare.
1881 Thessaly and Arta were annexed to the Greek state.
1885 A Romanian school was founded, for the teaching of the Romanian language.
1890 In January 2, the Averofeio School of Metsovo opened thanks to a donation from Georgios Averoff. The school was burnt down during the Civil War in October 1947 and the current Primary School was built in its place in 1955 (by the Tossizza Foundation).
1899 After Georgios Averoff died in 1899, a large part of his fortune was given to Metsovo.
1908 The Young Turk movement.
1910 An epidemic decimates the population of Metsovo.
1912 The First Balkan War breaks out in October 5, 1912.
1912 In October 31, the Greek army frees Metsovo, leading to the end of Ottoman rule in the area.
1913 1913-1939: GREEK STATE
1913 In August 10, the Treaty of Bucharest was signed and the Balkan Wars end.
1915 1915-7: National Schism between Venizelos and Constantine regarding Greece joining World War I.
1917 On May 27, Italian troops from the European alliance occupied Metsovo.
1917 On June 27, Greece joined the war after Constantine abdicated and left the country.
1923 On July 24, the Treaty of Lausanne was signed, calling for a population exchange between Greece and Turkey. The exchange did not apply to the Muslim Cham Albanians of Epirus.
1924 The Exarchate of Metsovo was abolished.
1936 A motorway connecting Thessaly with Epirus through the 'Katara pass' was completed.
1937 The Cultural Association of Metsovo was founded; its president was Gregoris Tsanakas, the vice-president was Evangelos Averoff.
1938 On August 25, the School of Textile and Carpet Weaving was inaugurated at the Toulis Orphanage. Ethnologist A. Hatzimihali also participated in the initiative to found the school.
1940 1940-1949: WORLD WAR II AND CIVIL WAR
1940 On October 29, the Greek-Italian War broke out.
1941 On April 27, German troops entered Athens. Greece was now under triple Occupation by the Germans, Italians and Bulgarians.
1941 In 1941-1942, Italy planned the foundation of an Autonomous Koutsovlach "Principality of Epirus".
1943 In July, Italian planes bombarded Metsovo
1943 In October, German troops entered Metsovo.
1944 In October, the occupation troops withdrew from Greece.
1947 On October 18-24 and November 3-6, during the Civil War, there were battles in Metsovo. The Democratic Army of Greece fails to occupy Metsovo.
1947 The Baron Michael Tossizza Foundation was officially created. Thanks to Evangelos Averoff's guidance, the Foundation played a key role in Metsovo’s economic growth and revival.
1950 1950-1974: POST-WAR PERIOD
1955 King Paul visited Metsovo to inaugurate the Folk Art Museum that had been built by the Baron Michael Tossizza Foundation.
1967 On April 21, a military dictatorship was established via a coup d'état.
1974 On July 24, the Dictatorship of the Colonels fell and democracy was restored.
1974 On December 8, the monarchy was dissolved via referendum.